Important Changes to the 2024 Prohibited List

Important changes in the individual classes of prohibited substances on the 2024 Prohibited List are presented below. Classes of the Prohibited List that do not contain any changes in 2024 compared to 2023 are not mentioned below.

SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION)

S2.2.1 was reworded under the heading of “Testosterone-stimulating peptides in males” for clarity. This specifies that buserelin, deslorelin, goserelin, histrelin, leuprorelin, nafarelin and triptorelin are examples of Gonadotrophin-Releasing Hormone (GnRH) agonist analogues, with histrelin added as a new example.
Kisspeptin and its agonist analogues, which act to stimulate GnRH secretion, and consequently testosterone, were also added.
S2.2.2 : Tetracosactide (ACTH 1-24) was added as an example, as it is the first 24 amino acid portion of natural corticotrophin (ACTH), and possesses the full biological activity of the natural hormone.
S2.2.4: Capromorelin and ibutamoren (MK-677) were added as examples of growth hormone secretagogues (GHS), which are mimetics of the natural hormone, ghrelin, that stimulates the production of growth hormone (GH) and, in turn, insulin-like growth factor 1 (IGF-1).
S2.3: The INN name for recombinant human IGF-1, mecasermin, was added.

Important Changes to the 2024 Prohibited List

SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION)

S0. Non-Approved Substances

S1. Anabolic Agents

S2. Peptide Hormones, Growth Factors, Related Substances, and Mimetics

S4. Hormone and Metabolic Modulators

S5. Diuretics and Masking Agents

M1. Manipulation of Blood and Blood Components